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3,5-Diiodo-L-thyronine

  • CAS:1041-01-6
  • purity:99%
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3,5-Diiodo-L-thyronine GMP Manufacturer Global Trade 1041-01-6 with Fast Delivery

  • Molecular Formula: C15H13I2NO4
  • Molecular Weight: 525.082
  • Appearance/Colour: Off-white solid 
  • Vapor Pressure: 2.39E-13mmHg at 25°C 
  • Melting Point: 255-260 °C (dec.) 
  • Refractive Index: 1.726 
  • Boiling Point: 559.4 °C at 760 mmHg 
  • PKA: 2.15±0.30(Predicted) 
  • Flash Point: 292.1 °C 
  • PSA: 92.78000 
  • Density: 2.095 g/cm3 
  • LogP: 4.04840 

3,5-Diiodo-L-thyronine(Cas 1041-01-6) Usage

Flammability and Explosibility

Notclassified

Pharmacology

3,5-Diiodo-L-thyronine is a?thyroid hormone with a l-thyroxine-like activity.

Purification Methods

Recrystallise it from EtOH. [Chambers et al. J Chem Soc 3424 1949, Beilstein 14 II 226, 14 III 1565, 14 IV 2372.]

InChI:InChI=1/C15H13I2NO4/c16-11-5-8(7-13(18)15(20)21)6-12(17)14(11)22-10-3-1-9(19)2-4-10/h1-6,13,19H,7,18H2,(H,20,21)

1041-01-6 Relevant articles

Improved method for synthesizing L-thyroxine sodium

-

Paragraph 0041; 0051; 0052; 0053; 0054; 0070; 0071, (2019/06/11)

The invention relates to an improved met...

Preparation method of levothyroxine sodium

-

Paragraph 0009; 0034; 0035, (2019/06/05)

The invention belongs to the field of ph...

Reductive dehalogenation and dehalogenative sulfonation of phenols and heteroaromatics with sodium sulfite in an aqueous medium

Tomanová, Monika,Jedinák, Luká?,Canka?, Petr

supporting information, p. 2621 - 2628 (2019/06/03)

Prototropic tautomerism was used as a to...

The synthesis of 13C9-15N-labeled 3,5-diiodothyronine and thyroxine

Hackenmueller, Sarah A.,Scanlan, Thomas S.

, p. 1439 - 1446 (2013/05/22)

Thyroid hormones undergo extensive metab...

1041-01-6 Process route

2-amino-3-(3,5-diiodo-4-(4-methoxyphenoxy)phenyl)propanoic acid
94345-95-6

2-amino-3-(3,5-diiodo-4-(4-methoxyphenoxy)phenyl)propanoic acid

3,5-diiodo-L-thyronine
1041-01-6,534-51-0,5563-89-3,299-82-1

3,5-diiodo-L-thyronine

Conditions
Conditions Yield
With hydrogenchloride; In water; at 100 ℃; for 5h; Temperature;
85.5%
N-acetyl-O-(4-methoxyphenyl)-3,5-diiodo-L-tyrosine ethyl ester
83249-56-3

N-acetyl-O-(4-methoxyphenyl)-3,5-diiodo-L-tyrosine ethyl ester

3,5-diiodo-L-thyronine
1041-01-6,534-51-0,5563-89-3,299-82-1

3,5-diiodo-L-thyronine

Conditions
Conditions Yield
With hydrogen iodide; acetic acid; at 120 ℃; for 4h; Reagent/catalyst; Temperature;
95.8%

1041-01-6 Upstream products

  • 94298-44-9
    94298-44-9

    N -formyl-3,5-diiodo-L-thyronine

  • 54337-43-8
    54337-43-8

    1-oxaspiro[2.5]octa-4,7-dien-6-one

  • 300-39-0
    300-39-0

    3,5-diiodo-l-tyrosine

  • 623-05-2
    623-05-2

    (4-hydroxyphenyl)methanol

1041-01-6 Downstream products

  • 51-48-9
    51-48-9

    L-thyroxine

  • 6893-02-3
    6893-02-3

    triiodothyronine

  • 1596-67-4
    1596-67-4

    O-(4-hydroxyphenyl)-3,5-diiodo-L-tyrosine

  • 203585-45-9
    203585-45-9

    3,5-diiodo-L-thyronine methyl ester

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